Okeeffes ' roots go back more than 20 years to an arid region on the California-Oregon border known as Klamath Basin. Bill O'Keeffe was a diabetic farmer who loved his hard physical work. However, the difficult lifestyle took its toll on his hands and feet. Seeing the discomfort caused by her chronically dry skin, her daughter, Tara, decided to find a solution. Applying her skills as a pharmacist, Tara and her father spent years creating and testing various formulas mixed together in their kitchen until, many years later, she developed a product that worked better than any other. This was the base formula that gave rise to O'Keeffe's Working Hands and, several years later, O'Keeffe's for Healthy Feet.